Compatibility Information

Vaniply and Vanicream Compounding jars

 

 

Disclaimer: This data is provided for informational purposes only, representing the results of a study of product stability with various active pharmaceutical ingredients. It does not serve, and cannot be construed, as representation of guarantee of product performance. In all cases the pharmacist is advised to consult recognized pharmaceutical compendia and other sources for product formulation, characteristics and methods used, including stability. Pharmaceutical Specialties, Inc. makes no warranties or presentations with regard to the appropriateness of this product in any compounded formulation and is solely at the discretion and liability of the pharmacist and practitioner relationship

 

 

 

Compounding in Vanicream™ Skin Cream

Strength (%)

Organoleptic Measures

Estimated BUD

 Ascorbic acid  5, 10, 15, 20  Incompatible
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 N/A
 Benzoyl Peroxide  Compatible Not tested. Assign BUD according to USP <795>
 Cade Oil  Compatible Not tested. Assign BUD according to USP <795>
 Camphor  Compatible Not tested. Assign BUD according to USP <795>
 Clindamycin  Compatible Not tested. Assign BUD according to USP <795>
 Cromolyn sodium  4  Compatible
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 Tentative Expiration: 24 months
Dexamethasone sodium phosphate .4  Compatible
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Not stable under the conditions tested. Assign BUD according to USP <795>
Erythromycin Compatible Not tested. Assign BUD according to USP <795>
Estradiol 0.6 Compatible
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Tentative Expiry Date: 24 months
Glycolic acid 5, 10, 15, 20  Compatible
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 Tentative Expiry Date: 24 months
Hydroquinone 4 Incompatible
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N/A
Lactic Acid  Compatible Not tested. Assign BUD according to USP <795>
 Menthol  Compatible Not tested. Assign BUD according to USP <795>
Oil-in-water bases Compatible N/A
Oxybenzone Compatible Not tested. Assign BUD according to USP <795>
Phenol > 1 Incompatible N/A
Plastibase Compatible N/A
Progesterone 20 Compatible
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Tentative Expiry Date: 24 months
Resorcinol Compatible Not tested. Assign BUD according to USP <795>
Salicylic acid Compatible Not tested. Assign BUD according to USP <795>
Starch Compatible Not tested. Assign BUD according to USP <795>
Sulfur Compatible Not tested. Assign BUD according to USP <795>
 Tar and Tar products:
LCD
Crude coal tar
Ichthymol
Zetar
 Compatible Not tested. Assign BUD according to USP <795>
Testosterone 1,2  Compatible
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Tentative Expiry Date: 24 months
Tretinoin 0.05  Compatible Not tested. Assign BUD according to USP <795>
Triamcinolone acetonide 0.025, 0.1, 0.5  Compatible
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Tentative Expiry Date: 24 months
Urea Compatible Not tested. Assign BUD according to USP <795>
Water Compatible N/A
Water-in-oil bases Incompatible N/A
Zinc Oxide Compatible Not tested. Assign BUD according to USP <795>

 

Compounding in Vaniply™ Ointment

Strength (%)

Organoleptic Measures

Estimated BUD

 Ascorbic acid  5, 10, 15, 20  Compatible
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 Tentative Expiry Date: 24 months
Cromolyn sodium 4   Compatible
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Not stable under the conditions tested. Assign BUD according to USP <795>
Erythromycin Compatible Not tested. Assign BUD according to USP <795>
Estradiol 0.6 Compatible
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Tentative Expiry Date: 24 months
Hydrocortisone Compatible Not tested. Assign BUD according to USP <795>
Hydroquinone 4 Compatible
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Not stable under the conditions tested. Assign BUD according to USP <795>
Menthol Compatible Not tested. Assign BUD according to USP <795>
Phenol Compatible Not tested. Assign BUD according to USP <795>
Progesterone 20 Compatible
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Tentative Expiry Date: 24 months
Salicylic acid Compatible Not tested. Assign BUD according to USP <795>
Sulfur Compatible Not tested. Assign BUD according to USP <795>
 Tar and Tar products:
LCD
Coal tar
  Compatible Not tested. Assign BUD according to USP <795>
Testosterone 1,2 Compatible
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Tentative Expiry Date: 24 months
Tretinoin Compatible Not tested. Assign BUD according to USP <795>
Triamcinolone acetonide Compatible Not tested. Assign BUD according to USP <795>
Urea Compatible Not tested. Assign BUD according to USP <795>